Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1.

doi:10.1038/303396a0

Back to search

Article

Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1.

Nature - 1 Jan 2000

Hall A, Marshall C J, Spurr N K, Weiss R A

Abstract excerpt

A molecular clone containing part of the transforming gene from two human sarcoma cell lines, HT1080 and RD, has been obtained and shown to represent a new member of the human ras gene family. The transforming gene has undergone no major rearrangements and has not been amplified in either sarcoma...

Topics

Alleles
Animals
Base Sequence
Cell Line
Cells, Cultured
Chromosome Mapping
Chromosomes, Human, 1-3
Cloning, Molecular
DNA Restriction Enzymes
Humans
Hybrid Cells
Mice
Oncogenes
RNA, Neoplasm
Sarcoma
Transfection

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.