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Article

Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product.

1 Feb 1993

Abstract excerpt

Using an expression cDNA cloning approach, we examined human tumor cell lines for novel oncogenes that might evade detection by conventional techniques. We isolated a transforming sequence that was highly efficient in transforming NIH 3T3 mouse fibroblasts. DNA sequence analysis identified the gene as the human homolog of a recently cloned alpha subunit of mouse GTP-binding protein G alpha 12. NIH 3T3 cells...

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Identifiers

PMID: 8423800
DOI: 10.1128/mcb.13.2.762

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Source receipt: pubmed, retrieved 7 Sept 2026.

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