Article

The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts.

1991-07-01

Abstract excerpt

A set of genes is rapidly inducible when quiescent fibroblasts are stimulated by growth factors or by the activation of temperature-sensitive retroviral protein-tyrosine kinases. Most of these so-called immediate-early genes were cloned by differential cDNA hybridization. DNA sequence analysis identified many of them as putative members of the growth factor or of the transcription factor gene family, suggesting a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: eea29918-b6a7-584d-bc5a-1e8628e74146
DOI: 10.1128/mcb.11.7.3682

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts.DOI 10.1128/mcb.11.7.3682Read

The stimulation of quiescent rat fibroblasts by v-src and v-fps oncogenic protein-tyrosine kinases leads to the induction of a subset of immediate early genes.Semantic proximity Read

Transactivation of c-fos and beta-actin genes by raf as a step in early response to transmembrane signals.Semantic proximity Read

Role of Rac GTPase in the nuclear signaling by EGF.Semantic proximity Read

Mitogenesis by v-Src: fluctuations throughout G1 of classical immediate early AP-1 and mitogen-activated protein kinase responses that parallel the need for the oncoprotein.Semantic proximity Read

CrkII induces serum response factor activation and cellular transformation through its function in Rho activation.Semantic proximity Read

A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts.Semantic proximity Read

Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway.Semantic proximity Read

LUCA15, a putative tumour suppressor gene encoding an RNA‐binding nuclear protein, is down‐regulated in ras‐transformed Rat‐1 cellsSemantic proximity Read

Transcriptional activation of the small GTPase gene rhoB by genotoxic stress is regulated via a CCAAT element.Semantic proximity Read

v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines.Semantic proximity Read

Transformation of rabbit vascular smooth muscle cells by transfection with the early region of SV40 DNA.Semantic proximity Read

An inhibitory Raf-1 mutant suppresses expression of a subset of v-raf-activated genes.Semantic proximity Read