Article
The c-Harvey-ras-1 oncogene in chromosome mediated gene transfer.
Anticancer research - 1 Jan 2000
Morten J E, Hirst M C, Porteous D J
Abstract excerpt
Transfection of DNA derived from a variety of tumours can induce morphological transformation of certain immortalised but normally contact-inhibited cell lines. This important technique has been instrumental in the identification and subsequent molecular cloning of a number of oncogenes, including Harvey-ras. We can extend this approach for studying neoplastic potential by performing chromosome-mediated, as...
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