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Article

A Case of IDH-Mutant Astrocytoma Harboring an IDH2 R172_H173delinsSN Variant.

Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Apr 2026

Auen Thomas, Chen Jie, Shonka Nicole, Cathcart Sahara

Abstract excerpt

IDH-mutant gliomas most commonly harbor the canonical IDH1 p.R132H mutation, followed by less common mutations involving IDH1 p.R132 or IDH2 p.R172 codons. We present a case of a 32-year-old male found to have a left temporal brain tumor with regional enhancement on brain MRI, for which he underwent resection. Histologic sections showed an infiltrating astrocytic tumor with increased mitotic activity and elevated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41736408
DOI: 10.1111/neup.70048
PMCID: PMC12933006

Genes

IDH2
IDH1
ATRX
MGMT
MIB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

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