Article

Genomic profiles of IDH-mutant gliomas: MYCN amplified IDH-mutant astrocytoma had the worst prognosis

2023-01-12

Abstract excerpt

This studyprogression-freene the genetic landscape and prognostic factor of IDH-mutant gliomas. Next-generation sequencing (NGS) using a brain tumor-targeted gene panel, methylation profiles, and clinicopathological features were analyzed for O_IDH_mut (n = 74) in 70 patients and for A_IDH_mut (n = 95) in 90 patients. 97.3% of O_IDH_mut and 98.9% of A_IDH_mut displayed a classic genomic landscape. CIC and/or FUBP1...

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Literature Corpus work: 8ef0e4b5-16a8-59b5-becd-50a15b0c9963
DOI: 10.21203/rs.3.rs-2437484/v1

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