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IDH-mutant astrocytoma with EGFR amplification—Genomic profiling in four cases and review of literature

1 Jan 2022

Abstract excerpt

IDH-mutant astrocytomas carry significantly better prognosis compared to their IDH-wildtype grade 4 (glioblastoma) counterpart. Several molecular diagnostic markers have emerged in the 2021 CNS WHO classification, with powerful prognostic implications to consider when classifying diffuse IDH-mutant astrocytomas.1–3EGFR amplification status, associated with aggressive glioma behavior4 and now regarded as a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35669011
DOI: 10.1093/noajnl/vdac067

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