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Article

IDH-mutant diffuse gliomas: tips and tricks in the era of genomic tumor classification.

Histology and histopathology - 1 Jul 2023

Ammendola Serena, Broggi Giuseppe, Barresi Valeria

Abstract excerpt

According to the fifth edition of the World Health Organization (WHO) Classification, diffuse gliomas typically occurring in adults are classified as oligodendroglioma IDH-mutant and 1p/19q codeleted, astrocytoma IDH-mutant, and glioblastoma IDH-wildtype. Among these, the former has the most favorable clinical course, whereas the latter has the worst prognosis. In IDH-mutant gliomas, the IDH1 p. R132H is the most...

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PMID: 36651583
DOI: 10.14670/HH-18-582

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