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Article

New Molecular Considerations for Glioma: IDH, ATRX, BRAF, TERT, H3 K27M.

Current neurology and neuroscience reports - 1 Feb 2017

Karsy Michael, Guan Jian, Cohen Adam L, Jensen Randy L, Colman Howard

Abstract excerpt

PURPOSE OF REVIEW: This review will discuss the role of several key players in glioma classification and biology, namely isocitrate dehydrogenase 1 and 2 (IDH1/2), alpha thalassemia/mental retardation syndrome X-linked (ATRX), B-Raf (BRAF), telomerase reverse transcriptase (TERT), and H3K27M. RECENT FINDINGS: IDH1/2 mutation delineates oligoden-droglioma, astrocytoma, and secondary glioblastoma (GBM) from primary...

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Source

Identifiers

PMID: 28271343
DOI: 10.1007/s11910-017-0722-5

Genes

ATRX
TERT
BRAF
IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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