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Starting DNA Synthesis: Initiation Processes during the Replication of Chromosomal DNA in Humans

14 Mar 2024

Abstract excerpt

The initiation reactions of DNA synthesis are central processes during human chromosomal DNA replication. They are separated into two main processes: the initiation events at replication origins, the start of the leading strand synthesis for each replicon, and the numerous initiation events taking place during lagging strand DNA synthesis. In addition, a third mechanism is the re-initiation of DNA synthesis after...

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PMID: 38540419
DOI: 10.3390/genes15030360

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