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Article

Host sex disparity and viral genotype dependence of the glycosylation level of small Hepatitis B surface protein in patients with HBeAg-positive chronic Hepatitis B.

Virology journal - 19 Jul 2023

Ou Guomin, Zhao Chengyu, Deng Juan, Zhuang Hui, Xiang Kuanhui, Li Tong

Abstract excerpt

BACKGROUND: Hepatitis B surface antigen (HBsAg) consists of six components of large/middle/small HBs proteins (L/M/SHBs) with non-glycosylated (ng)- or glycosylated (g)- isomers at sN146 in their shared S domain. g-SHBs plays a crucial role in hepatitis B virus (HBV) secretion. However, the host and viral factors impacting sN146 status in natural HBV infection remain revealed mainly due to the technical...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glycosylation

Share to Hepatitis B, Chronic

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Share to Hepatitis B Surface Antigens

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Share to Membrane Proteins

Source

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Identifiers

PMID: 37468949
DOI: 10.1186/s12985-023-02096-x
PMCID: PMC10357594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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