Article
Mutation in the S gene of hepatitis B virus and anti-HBs subtype-nonspecificity contributed to the co-existence of HBsAg and anti-HBs in patients with chronic hepatitis B virus infection.
Journal of medical virology - 1 Aug 2017
Fu Xiaochun, Chen Jing, Chen Huijuan, Lin Jinpiao, Xun Zhen, Li Shiqi, Liu Can, Zeng Yongbin, Chen Tianbin, Yang Bin, Ou Qishui
Abstract excerpt
The mechanism for the co-existence of hepatitis B surface antigen (HBsAg) and antibodies to HBsAg (anti-HBs) in chronic HBV infected patients remains controversial. This study aimed to explore the role of HBV S gene mutation and anti-HBs subtype-nonspecificity in patients with simultaneous HBsAg/anti-HBs positivity. Chronic HBV infections with (n = 145, group I) and without (n = 141, group II) anti-HBs were...
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