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Article

N-glycosylation mutations within hepatitis B virus surface major hydrophilic region contribute mostly to immune escape.

Journal of hepatology - 1 Mar 2014

Yu De-Min, Li Xin-Hua, Mom Vannary, Lu Zhong-Hua, Liao Xiang-Wei, Han Yue, Pichoud Christian, Gong Qi-Ming, Zhang Dong-Hua, Zhang Yan, Deny Paul, Zoulim Fabien, Zhang Xin-Xin

Abstract excerpt

BACKGROUND & AIMS: HBV immune escape represents a challenge to prevention, diagnosis, and treatment of hepatitis B. Here, we analyzed the molecular and clinical characteristics of HBV immune escape mutants in a Chinese cohort of chronically infected patients. METHODS: Two hundred sixteen patients with HBsAg and anti-HBs were studied, with one hundred eighty-two HBV carriers without anti-HBs as a control group....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24239777
DOI: 10.1016/j.jhep.2013.11.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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