Article
Small surface antigen variants of HBV associated with responses to telbivudine treatment in chronic hepatitis B patients.
Antiviral therapy - 1 Jan 2017
Dong Hui, Zhou Bin, Kang Hui, Jin Weirong, Zhu Yongqiang, Shen Yan, Sun Jian, Wang Shengyue, Zhao Guoping, Hou Jinlin, He Yungang
Abstract excerpt
BACKGROUND: Nucleoside/nucleotide analogues are widely used to treat chronic HBV infection, but drug resistance is common. The role of HBV surface gene variants in drug resistance to nucleoside/nucleotide analogues is unknown. We are trying to investigate the dynamics of S gene mutations and how they relate to a patient's virological response in this study. METHODS: Thirty patients with chronic hepatitis B were...
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