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Article

N-Linked Glycosylation at an Appropriate Position in the Pre-S2 Domain Is Critical for Cellular and Humoral Immunity against Middle HBV Surface Antigen.

The Tohoku journal of experimental medicine - 1 Jun 2015

Liu Hao, Wang Shixia, Jia Yiqiong, Li Jun, Huang Zuhu, Lu Shan, Xing Yiping

Abstract excerpt

Infection with hepatitis B virus (HBV) remains a worldwide health problem, and DNA-based vaccines against HBV have been tested for therapeutic applications. HBV possesses three envelope lipoproteins that are translated from a single reading-frame: large, middle, and small HBV surface antigens. Among these envelope proteins, the middle HBV surface antigen (MHBs) contains a constitutive N-linked glycosylation site...

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Source

Identifiers

PMID: 26062906
DOI: 10.1620/tjem.236.131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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