Article
Comparative characterization of hepatitis B virus surface antigen derived from different hepatitis B virus genotypes.
Virology - 1 Feb 2017
Hassemer Matthias, Finkernagel Malin, Peiffer Kai-Henrik, Glebe Dieter, Akhras Sami, Reuter Andreas, Scheiblauer Heinrich, Sommer Lisa, Chudy Michael, Nübling C Micha, Hildt Eberhard
Abstract excerpt
For human hepatitis B virus eight distinct and two candidate genotypes are described. These genotypes differ with respect to geographic distribution, molecular virology and virus-associated pathogenesis. Comparative analysis of HBV genotypes revealed, with exception of HBV/G that shows impaired HBsAg release, that no fundamental disparities between genotypes exist regarding glycosylation, subcellular...
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