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Serum O-glycosylated HBsAg levels correlate with HBV RNA in HBeAg positive CHB patients during antiviral therapy.

Antiviral research - 1 Feb 2025

Yao Bilian, Xu Qi, Yamada Yousuke, Angata Kiyohiko, Zhang Yan, Narimatsu Hisashi, Yu Demin, Zhang Xinxin

Abstract excerpt

BACKGROUND: Recent evidence has indicated that the O-glycosylated PreS2 domain of the middle HBsAg is a distinguishing characteristic that allows the identification of HBsAg of HBV Dane particles and SVPs. This study's objective was to assess the changes in serum O-glycosylated HBsAg levels in CHB patients undergoing ETV or Peg-IFNα treatment. METHODS: Our retrospective study enrolled 86 patients with genotype C...

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Antiviral Agents
DNA, Viral
Glycosylation
Hepatitis B, Chronic
Hepatitis B e Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatitis B Surface Antigens

Hepatitis B virus

Interferon-alpha

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Identifiers

PMID: 39788207
DOI: 10.1016/j.antiviral.2025.106077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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