Article
[Research on applying genetic and environmental risk score in risk-adapted colorectal cancer screening].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 10 Jun 2023
Luo C Y, Zhang Y H, Lu M, Lu B, Cai J, Li N, Zhou Y Y, Luo J H, Zhang D D, Yang X Z, Chen H D, Dai M
Abstract excerpt
Objective: To evaluate the effectiveness of a risk-adapted colorectal cancer screening strategy constructed utilizing genetic and environmental risk score (ERS). Methods: A polygenic risk score (PRS) was constructed based on 20 previously published single nucleotide polymorphisms for colorectal cancer in East Asian populations, using 2 160 samples with MassARRAY test results from a multicenter randomized...
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