A risk prediction model for colorectal cancer using genome-wide association study-identified polymorphisms and established risk factors among Japanese: results from two independent case-control studies.

Abstract excerpt

Most genome-wide association studies of colorectal cancer (CRC) carried out to date have been in populations with European ancestry, and the extent to which the identified variants contribute as predictors of CRC among Japanese populations has not been clarified. We analyzed 23 genetic variants identified in previous genome-wide association studies in a derivation case-control study with 558 cases and 1116...

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