Article

Genetic prediction of colorectal cancer risk in six major ancestries provides insights to streamline practice screening guidelines

2026-08-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and objective</h4> Colorectal cancer (CRC) is the third leading cause of cancer deaths worldwide. Early identification of high-risk individuals allows targeted prevention and early detection. <h4>Design</h4> We constructed a polygenic risk score (PRS) for CRC risk using data from 1,448,354 individuals (103,401 cases). We evaluated its performance for identifying high-risk indivi...

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Literature Corpus work: ca0f6872-8819-5f30-ac16-3d82948c2101
DOI: 10.64898/2026.08.10.26360074

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