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Article

Exploration of O-GlcNAc transferase glycosylation sites reveals a target sequence compositional bias.

The Journal of biological chemistry - 1 May 2023

Chong P Andrew, Nosella Michael L, Vanama Manasvi, Ruiz-Arduengo Roxana, Forman-Kay Julie D

Abstract excerpt

O-GlcNAc transferase (OGT) is an essential glycosylating enzyme that catalyzes the addition of N-acetylglucosamine to serine or threonine residues of nuclear and cytoplasmic proteins. The enzyme glycosylates a broad range of peptide sequences and the prediction of glycosylation sites has proven challenging. The lack of an experimentally verified set of polypeptide sequences that are not glycosylated by OGT has...

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Identifiers

PMID: 36963488
DOI: 10.1016/j.jbc.2023.104629
PMCID: PMC10164912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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