Article

Review of Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols : A book edited by Alain Beck

2013-07-03

Abstract excerpt

The glycoform profile of a glycoprotein is non-templated, i.e., is not encoded within the genome or otherwise predetermined; however, it is estimated that ~50% of human genes having an open reading frame encode a –N-X-S/T- amino acid sequence, where X represents any amino acid other than proline, that comprises a potential site (sequon) for N-linked glycosylation of the translated protein. N-linked glycosylation i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9a9274a2-49eb-5e1d-9f06-4d4ae8d08dc9
DOI: 10.4161/mabs.25631
PMCID: PMC3851215

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Review of Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols : A book edited by Alain BeckDOI 10.4161/mabs.25631Read

Glycosylation Shapes the Efficacy and Safety of Diverse Protein, Gene and Cell TherapiesSemantic proximity Read

Glycosylation shapes the efficacy and safety of diverse protein, gene and cell therapiesSemantic proximity Read

A Chemoenzymatic Strategy for Site-Specific Glyco-Tagging of Native Proteins for the Development of BiologicalsSemantic proximity Read

Precision Glycoform Engineering: Combining plant and <i>in vitro</i> systems for tailored biopharmaceutical productionSemantic proximity Read

Glycosyltransferases as versatile tools to study the biology of glycansSemantic proximity Read

A library of structurally homogeneous human <i>N</i> -glycans synthesized from microbial oligosaccharide precursorsSemantic proximity Read

Bacterial protein N-glycosylation: new perspectives and applications.Semantic proximity Read

Solving glycosylation disorders: fundamental approaches reveal complicated pathways.Semantic proximity Read

Strategies and Tactics for the Development of Selective Glycan-Binding ProteinsSemantic proximity Read

Glycosyltransferases in human milk oligosaccharide synthesis: structural mechanisms and rational designSemantic proximity Read

High-throughput analysis of immunoglobulin G glycosylationSemantic proximity Read

Metabolic precision labeling enables selective probing of O-linked <i>N</i> -acetylgalactosamine glycosylationSemantic proximity Read