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Glycosylation Shapes the Efficacy and Safety of Diverse Protein, Gene and Cell Therapies

2023-03-03

Abstract excerpt

Over recent decades, therapeutic proteins have had widespread success in treating a myriad of diseases. Glycosylation, a near universal feature of this class of drugs, is a critical quality attribute that significantly influences the physical properties, safety profile and biological activity of therapeutic proteins. Optimizing protein glycosylation, therefore, offers an important avenue to developing more efficac...

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Literature Corpus work
14e6f88f-ce9e-5ab4-b6dd-8e724a3a7acc
DOI
10.20944/preprints202303.0072.v1
Open publication

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Glycosylation Shapes the Efficacy and Safety of Diverse Protein, Gene and Cell TherapiesDOI 10.20944/preprints202303.0072.v1
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