Article

Shotgun scanning glycomutagenesis: a simple and efficient strategy for constructing and characterizing neoglycoproteins

2020-06-29

Abstract excerpt

As a common protein modification, asparagine-linked ( N- linked) glycosylation has the capacity to greatly influence the biological and biophysical properties of proteins. However, the routine use of glycosylation at naïve sites as a strategy for engineering proteins with advantageous properties is currently limited by our inability to construct large collections of glycoproteins for interrogating the structural...

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Literature Corpus work: 0bebf0b3-2bdb-591b-9d34-ca109b76bb73
DOI: 10.1101/2020.06.28.176198

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