Article
Genome- and transcriptome-wide association studies show that pulmonary embolism is associated with bone-forming proteins.
Expert review of hematology - 1 Oct 2022
Feng Ruoyang, Lu Mengnan, Yang Yanni, Luo Pan, Liu Lin, Xu Ke, Xu Peng
Abstract excerpt
BACKGROUND: Pulmonary embolism (PE) is a leading cause of death in stroke patients and a severe health burden worldwide. There is a pressing need to understand the mechanisms by which it occurs and to identify at-risk patients efficiently and accurately. METHODS: First, based on data from GWAS in European populations, we performed a linkage disequilibrium score regression (LDSC) analysis of plasma proteins and PE...
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