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Article

A genome-wide association study of the Protein C anticoagulant pathway.

PloS one - 1 Jan 2011

Athanasiadis Georgios, Buil Alfonso, Souto Juan Carlos, Borrell Montserrat, López Sonia, Martinez-Perez Angel, Lathrop Mark, Fontcuberta Jordi, Almasy Laura, Soria José Manuel

Abstract excerpt

The Protein C anticoagulant pathway regulates blood coagulation by preventing the inadequate formation of thrombi. It has two main plasma components: protein C and protein S. Individuals with protein C or protein S deficiency present a dramatically increased incidence of thromboembolic disorders. Here, we present the results of a genome-wide association study (GWAS) for protein C and protein S plasma levels in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22216198
DOI: 10.1371/journal.pone.0029168
PMCID: PMC3247258

Genes

DNAJC6
PROCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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