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Article

Molecular Research in Chronic Thromboembolic Pulmonary Hypertension

12 Feb 2019

Abstract excerpt

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a debilitating disease, for which the underlying pathophysiological mechanisms have yet to be fully elucidated. Occurrence of a pulmonary embolism (PE) is a major risk factor for the development of CTEPH, with non-resolution of the thrombus being considered the main cause of CTEPH. Polymorphisms in the α-chain of fibrinogen have been linked to resistance to...

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PMID: 30759794
DOI: 10.3390/ijms20030784

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