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Article

Evaluating the causal effects of circulating plasma proteins on the risk of malignant neoplasms of bone and articular cartilage.

The Journal of international medical research - 1 Feb 2026

Wang Yun, Zhou Ruhao, Wu Zhuangzhuang, Lv Zhi

Abstract excerpt

BackgroundMalignant neoplasms of bone and articular cartilage represent a rare group of highly invasive tumours with a poor prognosis, whose molecular mechanisms remain incompletely understood. Systematic identification of potential pathogenic proteins holds significance for early diagnosis and targeted therapy.MethodsA genetic tool was constructed using nine large-scale cis-protein quantitative trait loci (pQTL)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cartilage, Articular

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 41719433
DOI: 10.1177/03000605261416727
PMCID: PMC12924995

Genes

ADAMTS5
GNLY
PCSK7
CNTN1
CXCL16
PDCD1LG2
SCG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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