Article
Haptoglobin Induces a Specific Proteomic Profile and a Mature-Associated Phenotype on Primary Human Monocyte-Derived Dendritic Cells.
International journal of molecular sciences - 21 Jun 2022
Torres Alfredo, Vivanco Sheilah, Lavín Francisca, Pereda Cristián, Chernobrovkin Alexey, Gleisner Alejandra, Alcota Marcela, Larrondo Milton, López Mercedes N, Salazar-Onfray Flavio, Zubarev Roman A, González Fermín E
Abstract excerpt
Damage-associated molecular patterns (DAMPs) play a critical role in dendritic cells (DCs) ability to trigger a specific and efficient adaptive immune response for different physiological and pathological scenarios. We have previously identified constitutive DAMPs (HMGB1 and Calreticulin) as well as new putative inducible DAMPs such as Haptoglobin (HP), from a therapeutically used heat shock-conditioned melanoma...
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