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Article

HAMLET a human milk protein-lipid complex induces a pro-inflammatory phenotype of myeloid cells.

European journal of immunology - 1 Apr 2021

Vansarla Goutham, Håkansson Anders P, Bergenfelz Caroline

Abstract excerpt

HAMLET is a protein-lipid complex with a specific and broad bactericidal and tumoricidal activity, that lacks cytotoxic activity against healthy cells. In this study, we show that HAMLET also has general immune-stimulatory effects on primary human monocyte-derived dendritic cells and macrophages (Mo-DC and Mo-M) and murine RAW264.7 macrophages. HAMLET, but not its components alpha-lactalbumin or oleic acid,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33348422
DOI: 10.1002/eji.202048813
PMCID: PMC8248127

Genes

CD14
CD83
CD86
MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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