Article

Malaria-derived hemozoin alters chromatin remodelling and skews dendritic cell responses to subsequent bacterial infections

2024-03-19

Abstract excerpt

Hemozoin (HZ), the malaria pigment, is released together with the with the parasite merozoites during the blood stage of the disease, which is connected with the pro-inflammatory response to induce T-cells and B-cells. Co-infections with bacteria lead to a more severe disease progression and the underlying mechanisms are poorly understood. Here, we investigated the impact of HZ on the early response of monocyte-de...

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Literature Corpus work: a699db69-2985-520d-b655-2c3882879c61
DOI: 10.1101/2024.03.18.585548

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Malaria-derived hemozoin alters chromatin remodelling and skews dendritic cell responses to subsequent bacterial infectionsDOI 10.1101/2024.03.18.585548Read

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