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Article

Gene-inducing program of human dendritic cells in response to BCG cell-wall skeleton (CWS), which reflects adjuvancy required for tumor immunotherapy.

Immunology letters - 15 May 2005

Ishii Kazuo, Kurita-Taniguchi Mitsue, Aoki Mikio, Kimura Toru, Kashiwazaki Yasuo, Matsumoto Misako, Seya Tsukasa

Abstract excerpt

Adjuvants induce the expression of a number of genes in dendritic cells (DCs), which facilitate effective antigen-presentation and cytokine/chemokine liberation. It has been accepted that the toll-like receptor (TLR) family governs the adjuvant activity in DCs. An adjuvant with a long history is mycobacteria in an oil-in-water emulsion, namely Freund's complete adjuvant. Since the active center for the adjuvancy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15860229
DOI: 10.1016/j.imlet.2004.12.002

Genes

CCL20
CXCL10
CXCL5
EHD1
IFITM1
ISG15
MMP1
OASL
PTGS2
SOD2
TNF
TNFAIP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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