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Article

HSP27: an anti-inflammatory and immunomodulatory stress protein acting to dampen immune function.

Novartis Foundation symposium - 1 Jan 2008

Miller-Graziano Carol L, De Asit, Laudanski Krzysztof, Herrmann Tara, Bandyopadhyay Sanjukta

Abstract excerpt

The effects of HSP27 on human monocytes (MO) are predominantly antiinflammatory through preferential interleukin (IL)10 induction and by alteration of MO to immature dendritic cells (iDCs) or MO to macrophage (Mac) differentiation. Initial HSP27 inclusion in IL4+GM-CSF MO to iDC induction cultures allows Mac differentiation (CD14++, CD16+), decreases iDC (CD1a+) differentiation, and depresses DC induction of...

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Identifiers

PMID: 18575275
DOI: 10.1002/9780470754030.ch15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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