Article
Stimulation of dendritic cells by DAMPs in ALA-PDT treated SCC tumor cells.
Oncotarget - 29 Dec 2015
Wang Xiaojie, Ji Jie, Zhang Haiyan, Fan Zhixia, Zhang Linglin, Shi Lei, Zhou Feifan, Chen Wei R, Wang Hongwei, Wang Xiuli
Abstract excerpt
Photodynamic therapy (PDT) not only kills tumor cells directly but also rapidly recruits and activates immune cells favoring the development of antitumor adaptive immunity. It is believed that Topical 5-aminolevulinic acid mediated photodynamic therapy (ALA-PDT) can induce anti-tumor immune responses through dangerous signals damage-associated molecular patterns (DAMPs). In this study, we investigated the effect...
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