Article
A preliminary study on the activation and antigen presentation of hepatitis B virus core protein virus-like particle-pulsed bone marrow-derived dendritic cells.
Molecular bioSystems - 1 Nov 2010
Ding Fei-Xiang, Xian Xian, Guo Ying-Jun, Liu Yin, Wang Yue, Yang Fu, Wang Yu-Zhao, Song Shu-Xia, Wang Fang, Sun Shu-Han
Abstract excerpt
Hepatitis B virus core protein virus-like particles (HBc-VLPs) act as a strong immunogen and are suitable for uptake by dendritic cells (DCs), in which they directly promote DC maturation and migration. To illustrate the utility of global proteomic analysis techniques in elucidating the molecular events that are altered in HBc-VLP-pulsed bone marrow-derived DCs (BMDCs) and to gain a better understanding of the...
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