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A polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening

12 Apr 2022

Abstract excerpt

Abstract Polygenic risk scores (PRS) have the potential to identify individuals at risk of diseases, optimizing treatment, and predicting survival outcomes. Here, we construct and validate a genome-wide association study (GWAS) derived PRS for nasopharyngeal carcinoma (NPC), using a multi-center study of six populations (6 059 NPC cases and 7 582 controls), and evaluate its utility in a nested case-control study....

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PMID: 35414057
DOI: 10.1038/s41467-022-29570-4

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