Article
Elevated antibodies against Epstein-Barr virus among individuals predicted to carry nasopharyngeal carcinoma susceptibility variants.
The Journal of general virology - 1 Sept 2018
Coghill Anna E, Hsu Wan-Lun, Yang Qi, Wang Cheng-Ping, Lou Pei-Jen, Yu Kelly J, Yu Guoqin, Diehl Scott R, Chen Chien-Jen, Goldstein Alisa M, Hildesheim Allan
Abstract excerpt
Epstein-Barr virus (EBV) is an obligatory factor in the development of nasopharyngeal carcinoma (NPC), and anti-EBV IgA antibodies are elevated many years prior to the development of NPC. Nearly all adults are infected with EBV, but only a few develop cancer, suggesting that additional co-factors, including genetic susceptibility, must be required for the disease to manifest. Individuals were selected from the...
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