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Article

Epigenomic and Transcriptomic Prioritization of Candidate Obesity-Risk Regulatory GWAS SNPs.

International journal of molecular sciences - 23 Jan 2022

Zhang Xiao, Li Tian-Ying, Xiao Hong-Mei, Ehrlich Kenneth C, Shen Hui, Deng Hong-Wen, Ehrlich Melanie

Abstract excerpt

Concern about rising rates of obesity has prompted searches for obesity-related single nucleotide polymorphisms (SNPs) in genome-wide association studies (GWAS). Identifying plausible regulatory SNPs is very difficult partially because of linkage disequilibrium. We used an unusual epigenomic and transcriptomic analysis of obesity GWAS-derived SNPs in adipose versus heterologous tissues. From 50 GWAS and 121,064...

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Identifiers

PMID: 35163195
DOI: 10.3390/ijms23031271
PMCID: PMC8836216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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