Article
Phylogenetic analysis of combined lobular and ductal carcinoma of the breast.
Molecular medicine reports - 1 Oct 2021
Kobayashi Hiroko, Nakai Tokiko, Nakanishi Yoko, Esumi Mariko, Masuda Shinobu
Abstract excerpt
Breast cancer manifests in diverse forms, with particular reference to various cell types harboring different mutations and gene expression profiles. To elucidate the clonal relationship between cancer cells in tumors composed of both ductal and lobular phenotypes, two combined lobular and ductal carcinoma (CLDC) cases were analyzed, including one mixed ductal‑lobular carcinoma (MDL) lesion, by direct sequencing...
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