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Multi-omic characterization of ILC and ILC-like cell lines as part of ILC cell line encyclopedia (ICLE) defines new models to study potential biomarkers and explore therapeutic opportunities

2023-09-28

Abstract excerpt

Invasive lobular carcinoma (ILC), the most common histological “special type”, accounts for ∼10-15% of all BC diagnoses, is characterized by unique features such as E-cadherin loss/deficiency, lower grade, hormone receptor positivity, larger diffuse tumors, and specific metastatic patterns. Despite ILC being acknowledged as a disease with distinct biology that necessitates specialized and precision medicine treatm...

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Literature Corpus work: 1da1fa8d-698a-5d0e-949e-e1ffbb98e50d
DOI: 10.1101/2023.09.26.559548

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