Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multi-omic profiling of simultaneous ductal carcinoma in situ and invasive breast cancer.

Breast cancer research and treatment - 1 Jun 2024

Kaplan Henry G, Dowdell Alexa K, Berry Anna B, Shimol Racheli Ben, Robinson Fred L, Carney Christopher A, Piening Brian D

Abstract excerpt

PURPOSE: The progression of ductal carcinoma in situ (DCIS) to invasive breast carcinoma (IBC) in humans is highly variable. To better understand the relationship between them, we performed a multi-omic characterization of co-occurring DCIS and IBC lesions in a cohort of individuals. METHODS: Formalin-fixed paraffin-embedded tissue samples from 50 patients with co-occurring DCIS and IBC lesions were subjected to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Ductal, Breast
Share to Carcinoma, Intraductal, Noninfiltrating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Gene Expression Regulation, Neoplastic

Share to Genomics

Share to Multiomics

Share to Neoplasm Invasiveness

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 38523186
DOI: 10.1007/s10549-024-07270-5
PMCID: PMC11101558

Genes

ERBB2
KMT2C
MAP3K1
TP53
GATA3
MCL1
PIK3CA
SF3B1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multi-omic profiling of simultaneous ductal carcinoma in situ and invasive breast cancer.PMID 38523186Read ↗

A Molecular Portrait of High-Grade Ductal Carcinoma In Situ.Semantic proximity Read ↗

Comparable cancer-relevant mutation profiles in synchronous ductal carcinoma in situ and invasive breast cancer.Semantic proximity Read ↗

Intratumor Heterogeneity of Synchronous In Situ and Invasive Breast Carcinoma Revealed Using Multi-region Exome Sequencing.Semantic proximity Read ↗

Genomic Alterations during the In Situ to Invasive Ductal Breast Carcinoma Transition Shaped by the Immune SystemSemantic proximity Read ↗

Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer.Semantic proximity Read ↗

Genomic differences between pure ductal carcinoma in situ and synchronous ductal carcinoma in situ with invasive breast cancerSemantic proximity Read ↗

Genomic profiling defines variable clonal relatedness between invasive breast cancer and primary ductal carcinoma <i>in situ</i>Semantic proximity Read ↗

Progression from ductal carcinoma <i>in situ</i> to invasive breast cancer: RevisitedSemantic proximity Read ↗

A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progressionSemantic proximity Read ↗

Single-Cell Expression Analysis of Ductal Carcinoma In Situ Identifies Complex Genotypic-Phenotypic Relationships Altering Epithelial Composition.Semantic proximity Read ↗

The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situSemantic proximity Read ↗

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breastSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.