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Article

Comparable cancer-relevant mutation profiles in synchronous ductal carcinoma in situ and invasive breast cancer.

Cancer reports (Hoboken, N.J.) - 1 Jun 2020

Bergholtz Helga, Kumar Surendra, Wärnberg Fredrik, Lüders Torben, Kristensen Vessela, Sørlie Therese

Abstract excerpt

BACKGROUND: Ductal carcinoma in situ (DCIS) comprises a diverse group of preinvasive lesions in the breast and poses a considerable clinical challenge due to lack of markers of progression. Genomic alterations are to a large extent similar in DCIS and invasive carcinomas, although differences in copy number aberrations, gene expression patterns, and mutations exist. In mixed tumors with synchronous invasive...

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Source

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Identifiers

PMID: 32671987
DOI: 10.1002/cnr2.1248
PMCID: PMC7941529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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