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Article

Genome evolution in ductal carcinoma in situ: invasion of the clones

10 Nov 2016

Abstract excerpt

Ductal carcinoma in situ (DCIS) is the most frequently diagnosed early-stage breast cancer. Only a subset of patients progress to invasive ductal carcinoma (IDC), and this presents a formidable clinical challenge for determining which patients to treat aggressively and which patients to monitor without therapeutic intervention. Understanding the molecular and genomic basis of invasion has been difficult to study...

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PMID: 27861897
DOI: 10.1002/path.4840

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