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Article

Invasive lobular carcinoma of the breast: the increasing importance of this special subtype.

Breast cancer research : BCR - 7 Jan 2021

McCart Reed Amy E, Kalinowski Lauren, Simpson Peter T, Lakhani Sunil R

Abstract excerpt

Invasive lobular carcinoma (ILC) is the most common of the breast cancer special types, accounting for up to 15% of all breast cancer cases. ILCs are noted for their lack of E-cadherin function, which underpins their characteristic discohesive growth pattern, with cells arranged in single file and dispersed throughout the stroma. Typically, tumours are luminal in molecular subtype, being oestrogen and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33413533
DOI: 10.1186/s13058-020-01384-6
PMCID: PMC7792208

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