Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

kataegis: an R package for identification and visualization of the genomic localized hypermutation regions using high-throughput sequencing.

BMC genomics - 12 Jun 2021

Lin Xue, Hua Yingying, Gu Shuanglin, Lv Li, Li Xingyu, Chen Pin, Dai Peng, Hu Yunyun, Liu Anna, Li Jian

Abstract excerpt

BACKGROUND: Genomic localized hypermutation regions were found in cancers, which were reported to be related to the prognosis of cancers. This genomic localized hypermutation is quite different from the usual somatic mutations in the frequency of occurrence and genomic density. It is like a mutations "violent storm", which is just what the Greek word "kataegis" means. RESULTS: There are needs for a light-weighted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 34118871
DOI: 10.1186/s12864-021-07696-x
PMCID: PMC8196519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

kataegis: an R package for identification and visualization of the genomic localized hypermutation regions using high-throughput sequencing.PMID 34118871Read ↗

Katdetectr: An R/Bioconductor package utilizing unsupervised changepoint analysis for robust kataegis detectionSemantic proximity Read ↗

Katdetectr: an R/bioconductor package utilizing unsupervised changepoint analysis for robust kataegis detection.Semantic proximity Read ↗

Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGeneratorSemantic proximity Read ↗

Mutalisk: a web-based somatic MUTation AnaLyIS toolKit for genomic, transcriptional and epigenomic signatures.Semantic proximity Read ↗

Examining clustered somatic mutations with SigProfilerClustersSemantic proximity Read ↗

Examining clustered somatic mutations with SigProfilerClusters.Semantic proximity Read ↗

Clusters of Multiple Mutations: Incidence and Molecular Mechanisms.Semantic proximity Read ↗

Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator.Semantic proximity Read ↗

The Origins and Consequences of Localized and Global Somatic HypermutationSemantic proximity Read ↗

CMCS: classifying and analyzing clustered somatic mutations to elucidate the potential contributions in tumorigenesis.Semantic proximity Read ↗

SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational eventsSemantic proximity Read ↗

Identification of coding and non-coding mutational hotspots in cancer genomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.