Article
CMCS: classifying and analyzing clustered somatic mutations to elucidate the potential contributions in tumorigenesis.
The FEBS journal - 1 Feb 2026
Jin Jiaming, Zhao Xinmiao, Xiong Shizheng, Zhao Linjie, He Zhiheng, Zhang Yuting, Guo Haochuan, Gong Chengjun, Guo Li, Liang Tingming
Abstract excerpt
Clustered somatic mutations, which are common in cancer genomes and play critical roles in both pathological and physiological processes, are frequently accumulated in specific genomic regions. To enable efficient identification of these clustered mutations and gain insights into the potential functions of the associated genes in cancer, we developed the Cluster Mutation Classification System (CMCS;...
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