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Article

Mutalisk: a web-based somatic MUTation AnaLyIS toolKit for genomic, transcriptional and epigenomic signatures.

Nucleic acids research - 2 Jul 2018

Lee Jongkeun, Lee Andy Jinseok, Lee June-Koo, Park Jongkeun, Kwon Youngoh, Park Seongyeol, Chun Hyonho, Ju Young Seok, Hong Dongwan

Abstract excerpt

Somatic genome mutations occur due to combinations of various intrinsic/extrinsic mutational processes and DNA repair mechanisms. Different molecular processes frequently generate different signatures of somatic mutations in their own favored contexts. As a result, the regional somatic mutation rate is dependent on the local DNA sequence, the DNA replication/RNA transcription dynamics and epigenomic chromatin...

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Identifiers

PMID: 29790943
DOI: 10.1093/nar/gky406
PMCID: PMC6030918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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