Article

Examining clustered somatic mutations with SigProfilerClusters

2022-02-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Summary</h4> Clustered mutations are found in the human germline as well as in the genomes of cancer and normal somatic cells. Clustered events can be imprinted by a multitude of mutational processes, and they have been implicated in both cancer evolution and development disorders. Existing tools for identifying clustered mutations have been optimized for a particular subtype of clustered e...

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Literature Corpus work: f0aaff49-cef4-5123-8fe9-69fe63aced71
DOI: 10.1101/2022.02.11.480117

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