Article

Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator

2023-02-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> All cancers harbor somatic mutations in their genomes. In principle, mutations affecting between one and fifty base pairs are generally classified as small mutational events. Conversely, large mutational events affect more than fifty base pairs, and, in most cases, they encompass copy-number and structural variants affecting many thousands of base pairs. Prior studies have d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f5eee7c6-2374-51de-9654-ccc62bac08ad
DOI: 10.1101/2023.02.03.527015

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGeneratorDOI 10.1101/2023.02.03.527015Read

Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator.Semantic proximity Read

SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational eventsSemantic proximity Read

Interactive analysis of large cancer copy number studies with Copy Number Explorer.Semantic proximity Read

Examining clustered somatic mutations with SigProfilerClustersSemantic proximity Read

CNA Explorer and anaLyzer (CNAEL): an interactive web application and standard operating procedure enabling efficient clinical review and reporting of complex NGS-derived tumor copy number profilesSemantic proximity Read

Topography of mutational signatures in human cancerSemantic proximity Read

TarPan: an easily adaptable targeted sequencing panel viewer for research and clinical use.Semantic proximity Read

CANCERSIGN: a user-friendly and robust tool for identification and classification of mutational signatures and patterns in cancer genomesSemantic proximity Read

Regional Mutational Signature Activities in Cancer GenomesSemantic proximity Read

kataegis: an R package for identification and visualization of the genomic localized hypermutation regions using high-throughput sequencing.Semantic proximity Read

Examining clustered somatic mutations with SigProfilerClusters.Semantic proximity Read

Bioinformatic Methods to Identify Mutational Signatures in Cancer.Semantic proximity Read