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Article

Interaction between extracellular ATP5A1 and LPS alleviates LPS-induced neuroinflammation in mice.

Neuroscience letters - 27 Jul 2021

Yue Lingyun, Liu Pu, Ma Ningtian, Xu Yuxia, Zhu Cuiqing

Abstract excerpt

Neuroinflammation is one of the main causes of Alzheimer's disease (AD). The presence of Lipopolysaccharide (LPS) in senile plaques (SP) of AD suggests that it plays a role in AD pathogenesis. ATP5A1 (F1F0-ATP synthase F1 α subunit) is abundant in SP. Further, the protein has recently been found to have an anti-infection role in zebrafish embryos. In the present study, we observed that LPS levels were higher in...

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Identifiers

PMID: 34098024
DOI: 10.1016/j.neulet.2021.136005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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